<p>Active <em>Cousinia thomsonii</em> Extracts Modulate Expression of Crucial Proinflammatory Mediators/Cytokines and NFκB Cascade in Lipopolysaccharide-Induced Albino Wistar Rat Model</p>
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منابع مشابه
The Protective Effect of Silymarin on Lipopolysaccharide-Induced Liver Toxicity in Male Wistar Rat
Background and Aims: Lipopolysaccharide (LPS) triggers production of reactive oxygen species and inflammatory cytokines. Nowadays Silybum marianum has been shown to treat liver and gall bladder disorders, especially to protect the liver against poisoning from various toxins. Therefore, we decided to evaluate the protective effect of silymarin on LPS-induced liver toxicity in male Wistar rat. M...
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Objective(s): Gastric cancer is the first and second leading cause of cancer related death in Iranian men and women, respectively. Gastric cancer management is based on the surgery, radiotherapy and chemotherapy. In the present study, for the first time, the beneficial effect of saffron (Crocus sativus L.) aqueous extract (SAE) on the 1-Methyl-3-nitro-1-nitrosoguanidine (MNNG)-induced gastric c...
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The effects of aqueous extract of Tapinanthus bengwensis and Ocimum gratissimum treatment on Wistar Albino Rats actuated with diabetes by administration of streptozotocin (Zanosar) was investigated. Hypoglycemic properties were evaluated after treatment of groups of male and female rats weighing 240-300g with 5% and 10% extract of the herbs for 16 days resulted in significant (p<0.05) reduction...
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Ketamine may be advantageous for anesthesia of patients with sepsis caused by gram-negative bacteria, because ketamine may suppress LPS-induced production of proinflammatory cytokines, such as TNFα and IL-6. NFκB is an important transcription factor that is involved in the post-transcriptional regulation of mRNA expression for several immunoinflammatory mediators in response to endotoxemia. Thi...
متن کاملAge changes in the Wistar albino rat eye.
Over 200 rat eyes were enucleated for this study. The youngest rats were 21 days and the oldest 1,000 days old. All specimens were removed with as little trauma as possible and trimmed of adventitial tissue with small scissors and for ceps. Measurements were made with a small caliper having a micrometer adjust ment before the eyes were completely fixed, with the exception of the 1,000-day gro...
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ژورنال
عنوان ژورنال: Journal of Inflammation Research
سال: 2020
ISSN: 1178-7031
DOI: 10.2147/jir.s272539